School Seminars and Colloquia

Modelling protective anti-tumour immunity using a hybrid agent-based and delay differential equation approach

Continuum Modelling Seminar

by Dr Peter Kim

Institution: University of Sydney
Date: Thu 8th November 2012
Time: 12:00 PM
Location: Richard Berry-213

Abstract: Although cancers seem to consistently evade current medical
treatments, the body’s immune defences seem quite effective at
controlling incipient tumours. Understanding how our immune systems
provide such protection against early-stage tumours and how this
protection could be lost will provide insight into designing
next-generation immune therapies against cancer. To engage this
problem, we formulate a mathematical model of the immune response
against small, incipient tumours. The model considers the initial
stimulation of the immune response in lymph nodes and the resulting
immune attack on the tumour and is formulated as a hybrid agent-based
and delay differential equation model.