School Seminars and Colloquia

A Stochastic Model of Coupled Enzymatic Processing

Stochastic Processes and Financial Mathematics

by Professor Ruth Williams


Institution: Department of Mathematics, UCSD
Date: Wed 20th October 2010
Time: 3:15 PM
Location: Architecture-G19 (Sisalkraft Theatre), The University of Melbourne

Abstract: A major challenge for systems biology is to deduce 
the molecular interactions that underlie correlations
 observed between concentrations of different intracellular molecules.
While direct explanations such 
as coupled transcription or direct protein-protein 
interactions are often considered, potential indirect
 sources of coupling have received much less attention.

In this talk, I will report on an investigation,
 involving both a stochastic model and related experiments,
 of how correlations can arise generically from
 such an indirect coupling
mechanism involving the
 processing of multiple protein species by a common
 enzyme.



Based on joint work with Natalie Cookson, Tal Danino, Jeff
Hasty, Will Mather, Octavio Mondragon-Palomino,
 Lev Tsimring.

For More Information: contact: Prof Daniel Dufresne at dufresne@unimelb.edu.au OR Dr Aihua Xia at xia@ms.unimelb.edu.au